Guadalupe is one of the busiest place in Makati. It is located at the other side of Mandaluyong and only the Pasig River separate it. Since it is strategically along the EDSA or Epifanio Delos Santos Avenue, it became more busy. Also it is the gate to the residential place of Makati such Poblacion, Cembo, West Rembo, East Rembo and PemboIt is also the gateway to Pateros.
Aside from those, Guadalupe MRT Station also resides in here and some of the buildings located in it such as the Guada Mall. Jollibee, Mc Donalds.